医学
核医学
正电子发射断层摄影术
磁共振成像
生长抑素受体
放射科
PET-CT
全身成像
神经影像学
生长抑素
内科学
精神科
作者
GIUSEPPE EMMANUELE UMANA,GIANLUCA FERINI,MANDARA MURALIDHAR HARIKAR,TEJAS VENKATARAM,ROBERTA COSTANZO,GIANLUCA SCALIA,PAOLO PALMISCIANO,LAURA BRUNASSO,FEDERICA PAOLINI,ANDREA SCIORTINO,ROSARIO MAUGERI,ANTONIO CREA,FABIO BARONE,FRANCESCO INSERRA,VALERIO DA ROS,GIACOMO CUTTONE,GABRIELE CORSALE,CONCETTO CRISTAUDO,SEBASTIANO COSENTINO,MARIA GABRIELLA SABINI,MASSIMO IPPOLITO
标识
DOI:10.21873/anticanres.16095
摘要
One of the main limitations of standard imaging modalities is microscopic tumor extension, which is often difficult to detect on magnetic resonance imaging (MRI) and computer tomography (CT) in the early stages of the tumor. (68)Ga-DOTA(0)-Phe(1)-Tyr(3)-octreotide positron-emission tomography/computed tomography (68Ga-DOTATOC PET/CT) has shown efficacy in detecting lesions previously undiagnosed by neuroimaging modalities, such as MRI or CT, and has enabled the detection of multiple benign tumors (like multiple meningiomas in a patient presenting with a single lesion on MRI) or additional secondary metastatic locations.We retrospectively reviewed data from the Cannizzaro Hospital on brain and body 68Ga-DOTATOC PET/CT "incidentalomas", defined as tumors missed on CT or MRI scans, but detected on 68Ga-DOTATOC PET/CT scans. "Incidentalomas" were classified into "brain" and "body" groups based on their location. The standardized uptake values (SUVs) were compared between the two groups.A total of 61 patients with "incidentalomas" documented on the 68Ga-DOTATOC PET/CT were identified: 18 patients with 25 brain lesions and 43 patients with 85 body lesions. The mean SUV at baseline was 9.01±7.66 in the brain group and 14.8±14.63 in the body group.We present the first series on brain and body "incidentalomas" detected on 68Ga-DOTATOC PET/CT. Whole-body 68Ga-DOTATOC PET/CT may be considered in selected patients with brain tumors with high expression of somatostatin receptors to assist radiosurgical or surgical planning and, simultaneously, provide accurate follow-up with early detection of potential metastases.
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