Review on overview of colon targeting drug dilivery system

作者
Karishma Mahajan,Nishant Thakur,Kritika Thakur,. Simran
出处
期刊:Journal of emerging technologies and innovative research 卷期号:8 (2): 2120-2137-2120-2137
摘要

In field of medicine oral route is mostly used path for the administration of drug. so, the oral route is not preferred for lower GIT disorder. So, to overcome this problem drug directly targeting to the specific site. In this review article overview on the colon targeting drug delivery system. Colon is the site where drug is targeted on the local site and used for the local colon disease. Colon targeting drug delivery system not just for the local disease but also used for the systemic delivery of the drug such as proteins, therapeutic peptides, anti-asthmatic, anti-hypertensive drug, antidiabetic drug. Now a day number of method are used to formulate CTDDS such as formation of pro drug, coating of polymers etc. colon targeting drug delivery system is a new system for targeting a drug in specific site for enhance the therapeutic effect of poorly absorbed drug. And now a day drug targeted on colon through rectal route. But this route is very painful. In this article discuss about the anatomy of the colon, factor affecting the colon targeting drug delivery system, advantages of colon targeting drug delivery system, limitation of colon targeting drug delivery system and evaluation of the colon targeting drug delivery system. But in this review mainly discuss about the new method used for colon targeting drug delivery system such as Microspheres,carbon nanotube, metal nanoparticles etc

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