Are metal-based antibacterial gels a potential alternative for disinfection in contemporary endodontics?

Developing an antimicrobial gel is highly dependent upon numerous compositional factors, where development is still at the early stages. The use of copper nanoparticles appeared to be more appropriate for use in canal disinfection, compared with silver that also had higher levels of human cell toxicity. The ratios selected for the biocompatible polymers had a critical impact on the physical state, antimicrobial, and toxicity levels. At present, antimicrobial gels are not as effective as sodium hypochlorite.