Prediabetes and ischemic stroke

Prediabetes is a glucose metabolism status between normal glucose metabolism and diabetes. It can not only increase the risks of occurrence and recurrence of stroke, but also affect stroke outcomes. Prediabetes causes ischemic stroke mainly through the insulin resistance and blood-brain barrier damage. Non-drug or drug intervention in patients with prediabetes can delay progression from prediabetes to diabetes and reduce the risks of occurrence and recurrence of stroke. Key words: Stroke; Brain Ischemia; Diabetes Mellitus, Type 2; Prediabetic State; Glucose Intolerance; Recurrence; Secondary Prevention; Risk Factors; Hypoglycemic Agents