医学
体外
甲醇中毒
重症监护医学
甲醇
外科
有机化学
化学
作者
Darren M. Roberts,Chris Yates,Bruno Mégarbane,James F. Winchester,Robert MacLaren,Sophie Gosselin,Thomas D. Nolin,Valéry Lavergne,Robert S. Hoffman,Marc Ghannoum
标识
DOI:10.1097/ccm.0000000000000708
摘要
Extracorporeal treatment has a valuable role in the treatment of patients with methanol poisoning. A range of clinical indications for extracorporeal treatment is provided and duration of therapy can be guided through the careful monitoring of biomarkers of exposure and toxicity. In the absence of severe poisoning, the decision to use extracorporeal treatment is determined by balancing the cost and complications of extracorporeal treatment to that of fomepizole or ethanol. Given regional differences in cost and availability of fomepizole and extracorporeal treatment, these decisions must be made at a local level.
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