色酮
香豆素
化学
氟尿嘧啶
立体化学
有机化学
癌症
遗传学
生物
作者
Laura Giraldo-Arroyave,A.F. Yepes,Wilson Cardona‐G
出处
期刊:Molbank
[Multidisciplinary Digital Publishing Institute]
日期:2024-02-28
卷期号:2024 (1): M1779-M1779
被引量:1
摘要
A series of 5-fluorouracil/coumarin and 5-fluorouracil/chromone hybrids were synthesized with good yields using click chemistry as the key step. The structures of these compounds and all intermediates were elucidated by spectroscopic analysis. Furthermore, pharmacokinetic and drug-like computations taken together indicated that the novel hybrids have a strong possibility to advance to further biological studies.
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