Highly Sensitive Metamaterial Biosensor for Cancer Early Detection

A novel design of metamaterial biosensor for cancer early detection is proposed and analyzed. The suggested structure is based on two loops of hexagonal gold layers on a polyamide substrate. High field confinement is obtained in the sensing region with high absorption of 0.999 and high quality factor of 11.33 at f = 3.15 THz. The resonance frequency is sensitive to the sample refractive index variation. Therefore, high average sensitivity of 1649.8 GHz/RIU is achieved for cancer early detection through basal cell, breast cell, bervical cell, jurkat, MCF-7, and PC12. Further, high linear performance is obtained with good robustness against fabrication imperfection. The analysis is carried out using full vectorial finite element method.