Lv11
60 积分 2025-07-19 加入
Fluorocyclopropyl-Containing Tacrine Derivatives as Potent and Selective Dual CDK2/CDK9 Inhibitors for the Treatment of Colorectal Cancer
6分钟前
待确认
Kill Two Birds with One Stone: An Efficient and Potent AR CBS-Targeted Degrader Reverses Breast Cancer Resistance via Concurrent AR Degradation and ERα Transcriptional Suppression
9天前
已完结
Highly Specific Inhibition of c-Myc Oncogene Expression through Shifting the G-Quadruplex toward a Triplex Structure
9天前
已完结
HSP90 Mediates Targeted Degradation of Nonclient Protein PARP1 for Breast Cancer Treatment
1个月前
已完结
HSP90 Mediates Targeted Degradation of Nonclient Protein PARP1 for Breast Cancer Treatment
1个月前
已完结
Novel β-carboline derivatives show promise as dual-target inhibitors of DNA and TOP2A for the treatment of triple negative breast cancer
2个月前
已完结
N,N′-phosgenation with triphosgene in the synthesis of direct dyes containing the ureylene group
2个月前
已完结
NIS-Mediated Hofmann-Type Rearrangement to Acyl Isocyanates: A Novel Approach for N‑Acylurea Synthesis
2个月前
已完结
Design and synthesis of lactam analogues of andrographolide and discovery of their anticancer activity as dual EGFR and VEGFR2 inhibitors
3个月前
已关闭
发现 1-二氟甲基-3-(3-氰基苯基)-6-[4-(三氟甲氧基)苯基]咪唑[1,5-a]吡嗪-8-(7H)-酮作为治疗缺血性中风和心肌梗死的有效 P2Y1 拮抗剂。
3个月前
已完结