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300 积分 2022-10-06 加入
Molecular Insights on Selective and Specific Inhibitors of Cyclin Dependent Kinase 9 Enzyme (CDK9) for the Purpose of Cancer Therapy
1年前
已完结
CDK8 as a therapeutic target for cancers and recent developments in discovery of CDK8 inhibitors
1年前
已完结
Abstract DDT02-02: BAY 1143572: A first-in-class, highly selective, potent and orally available inhibitor of PTEFb/CDK9 currently in Phase I, inhibits MYC and shows convincing anti-tumor activity in multiple xenograft models by the induction of apoptosis
1年前
已关闭
Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target
1年前
已完结
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations
1年前
已完结
Identification of novel CDK 9 inhibitors based on virtual screening, molecular dynamics simulation, and biological evaluation
1年前
已完结
Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer
1年前
已完结
The Role of Statins in the Prevention of Ovarian and Endometrial Cancers
1年前
已完结
Toyocamycin induces apoptosis via the crosstalk between reactive oxygen species and p38/ERK MAPKs signaling pathway in human prostate cancer PC-3 cells
1年前
已完结
Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency
2年前
已完结
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