Lv32
220 积分 2025-09-09 加入
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
8小时前
待确认
Development of XYD113 as a potent and highly selective GSPT1 degrader for cancer therapy
9天前
已完结
Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice
10天前
已完结
Design, synthesis, and biological evaluation of novel selenium-matrine hybrid compounds as topo I -targeted anticancer agents
13天前
已完结
AI-guided multi-objective optimization identifies a Jelleine I-derived gram-negative antimicrobial peptide lead
14天前
已关闭
Discovery and optimization of diarylsulfone-based dual M3-Antagonists and β2-Agonists (MABAs) as inhaled bronchodilators
14天前
已关闭
Structure-based optimization of GSK2982772-derived RIPK1 inhibitors reveals the dispensability of the methylene linker and identifies a potent anti-necroptosis candidate for further optimization
15天前
已关闭
Discovery and optimization of diarylsulfone-based dual M3-Antagonists and β2-Agonists (MABAs) as inhaled bronchodilators
15天前
已关闭
A PROTAC-inspired bifunctional small molecule recruits CDK6 to target EYA2 degradation and suppress breast tumor growth
15天前
已完结
Preclinical evaluation of [225Ac]Ac-crown-TATE – An alpha-emitting radiopharmaceutical for neuroendocrine tumors
16天前
已完结
Tailoring porous structure in non-ionic polymer membranes using multiple templates for low-cost iron-lead single-flow batteries
3个月前
已采纳
Low-dose X-ray-activated radiodynamic therapy via a lutetium-coordinated nanoplatform synergizing PARP inhibition and ferroptosis
4个月前
已采纳
Effect of alfalfa supplementary change dietary non-fibrous carbohydrate (NFC) to neutral detergent fiber (NDF) ratio on rumen fermentation and microbial function in Gansu alpine fine wool sheep ( Ovis aries )
4个月前
已采纳
TNFSF10 drives hyperactive immune responses via NLRP3 inflammasome and endoplasmic reticulum stress in autoimmune and inflammatory diseases
5个月前
已采纳
Antibiotic-persistent bacterial cells exhibiting low-level ROS are eradicated by ROS-independent membrane disruption
5个月前
已采纳
Confinement-Induced One-Dimensional Magnetism in CrSBr Chains via Carbon Nanotube Encapsulation
5个月前
已采纳
Linear photogalvanic effects in monolayer ternary metallic compound Na2MgSn
6个月前
已采纳
The microbiota restrains neurodegenerative microglia in a model of amyotrophic lateral sclerosis
6个月前
已采纳
Effectiveness of brief online mindfulness-based intervention on different types of mobile phone addiction: mechanisms of influence of trait mindfulness
6个月前
已采纳
Ultra-high-throughput mapping of genetic design space
6个月前
已驳回
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