Lv11
80 积分 2025-04-17 加入
Discovery of Novel GPR119 Agonists with Improved Kinetic Solubility and Drug-like Properties for Type 2 Diabetes Treatment
8小时前
已完结
Discovery of Tetrasubstituted Quinazolin-4(3H)-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors
10天前
已完结
Design and Development of DNA Damage Chemical Inducers of Proximity for Targeted Cancer Therapy
16天前
已完结
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors
22天前
已完结
A patent review of PRMT5 inhibitors to treat cancer (2018 - present)
27天前
已完结
First-in-class dual inhibitors of MASTL and Aurora A kinase: Discovery of selective cyclohexa[b]thiophenes with potent anticancer activity
1个月前
已完结
Pt(IV) Complexes in the Search for Novel Platinum Prodrugs with Promising Activity
1个月前
已完结
Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure
1个月前
已完结
Linker Chemistry in Antibody–Drug Conjugates: Current Strategies, Clinical Pharmacokinetic Analyses, and Linker-Free Outlooks
1个月前
已完结
Trastuzumab Duocarmazine in Pretreated Human Epidermal Growth Factor Receptor 2–Positive Advanced or Metastatic Breast Cancer: An Open-Label, Randomized, Phase III Trial (TULIP)
2个月前
已完结
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