Lv1
80 积分 2025-04-17 加入
Discovery and Pharmacological Evaluation of Potent and Highly Selective PARP1 Inhibitors
17小时前
已完结
Design, Synthesis, and Pharmacodynamic Evaluation of Highly Selective PARP1 Inhibitors with Brain Penetrance
1天前
已完结
Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial
2天前
已完结
Selection of LRP1 ligand phage-displayed single domain antibody that transmigrates BBB
21天前
已完结
Systematic Evaluation of Position-Specific Tolerability of Seven Backbone and Ribose Modifications in Fully Chemically Stabilized siRNAs
23天前
已完结
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
26天前
已完结
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
29天前
已完结
Synthesis and bioevaluation of diaryl urea derivatives as potential antitumor agents for the treatment of human colorectal cancer
1个月前
已完结
Novel Triazoloquinoxaline-Based Tubulin Polymerization Inhibitor Induces Necroptosis and Significantly Inhibits Metastatic Melanoma Tumor Growth
1个月前
已完结
Rational Design of Potent and Orally Efficacious PI3Kα/δ Degrader for PIK3CA Mutant Breast Cancer without Hyperglycemic Liability
1个月前
已完结
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