Lv61
2620 积分 2025-01-05 加入
Discovery of YYSW001: A Highly Selective, Orally Bioavailable JAK1 Inhibitor Achieving Efficacy under a Moderate-Inhibition Strategy with Improved Preclinical Tolerability
6小时前
待确认
Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers
3天前
已完结
Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders
3天前
已完结
Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders
3天前
已完结
Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong in vivo Antitumor Activity
3天前
已完结
Stereoselective Access to Polypropionates Expedited by the Double Hydroboration of Allenes: Total Synthesis of Antitumor (−)-Pironetin
3天前
已完结
Antioxidants in anti‐Alzheimer's disease drug discovery
8天前
已完结
CXCR4/CXCL12 axis: “old” pathway as “novel” target for anti‐inflammatory drug discovery
8天前
已完结
Artificial Intelligence-Assisted Optimization of Antipigmentation Tyrosinase Inhibitors: De Novo Molecular Generation Based on a Low Activity Lead Compound
8天前
已完结
Synthetically Feasible De Novo Molecular Design of Leads Based on a Reinforcement Learning Model: AI-Assisted Discovery of an Anti-IBD Lead Targeting CXCR4
8天前
已完结
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