Lv5
845 积分 2021-01-06 加入
Discovery of HW201877: A Highly Potent and Orally Bioavailable Inhibitor of 15-Prostaglandin Dehydrogenase to Potentiate Tissue Repair and Regeneration
11小时前
待确认
A selective sodium channel blocker for acute pain
4个月前
已完结
Neutral LPAR1 Antagonists for the Treatment of Idiopathic Pulmonary Fibrosis
4个月前
已完结
Synthetic Approaches to the New Drugs Approved during 2023
4个月前
已完结
Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer
6个月前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
6个月前
已完结
MoA Studies of the TEAD P-Site Binding Ligand MSC-4106 and Its Optimization to TEAD1-Selective Amide M3686
6个月前
已完结
An updated patent review of SOS1 inhibitors (2022-present)
6个月前
已完结
Scalable Synthesis of ABBV-105 Enabled by Suzuki Coupling with Low Pd Loading, Ru-Catalyzed Asymmetric Hydrogenation, and Acylation Using Impinging Jet
11个月前
已完结
Abstract PO3-25-09: OKI-219, a PI3KαH1047R-mutant-selective inhibitor demonstrates efficacy as a single agent and drives combination responses with standard of care therapies in pre-clinical PI3KαH1047R mutant breast cancer models
1年前
已关闭
A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure
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