Lv72
3550 积分 2021-03-03 加入
Development of potent and selective CK1α Molecular Glue Degraders
19天前
已完结
Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library
20天前
已完结
On the relationship between hERG inhibition and the magnitude of QTc prolongation: An in vitro to clinical translational analysis
26天前
已完结
FFLOM: A Flow-Based Autoregressive Model for Fragment-to-Lead Optimization
28天前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
1个月前
已完结
Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition
1个月前
已完结
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
1个月前
已完结
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors
1个月前
已完结
Thiazole‐based IL‐17 inhibitors discovered by scaffold morphing
1个月前
已完结
Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models
1个月前
已完结
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