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180 积分 2025-03-26 加入
RIPTACs: A groundbreaking approach to drug discovery
5天前
已完结
Generation of Acsl4 Gene Knockout Mouse Model by CRISPR/Cas9-Mediated Genome Engineering
1个月前
已完结
Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain
1个月前
已完结
Cleavable linkers in antibody–drug conjugates
4个月前
已完结
BRAF oncogenic mutants evade autoinhibition through a common mechanism
4个月前
已完结
Encoding BRAF inhibitor functions in protein degraders
4个月前
已完结
Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor
4个月前
已完结
Discovery of a potent and selective JAK1-targeting PROTAC degrader with anti-tumor activities
4个月前
已完结
Challenges, opportunities and therapeutic potential of JAK inhibitors and their derived PROTACs (2022 – 2023)
4个月前
已完结
Mutated APC and Asef are involved in the migration of colorectal tumour cells
5个月前
已完结
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