Lv6
2300 积分 2023-01-17 加入
Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia
1天前
已完结
Discovery of a Highly Potent and Selective Tyrosine Kinase 2 (TYK2) Degrader with In Vivo Therapeutic Efficacy in a Murine Psoriasis Model
1个月前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
1个月前
已完结
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
1个月前
已完结
From KRAS G12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
1个月前
已完结
Practical and Scalable Method for Manufacturing AZD4604, A Potent and Selective JAK1 Inhibitor
1个月前
已完结
A patent review of anticancer CDK2 inhibitors (2017–present)
2个月前
已完结
Cyclin-dependent kinase 4/6 inhibitors for cancer therapy: a patent review (2015 – 2019)
2个月前
已完结
A patent review of small molecule CDK4/6 inhibitors in the treatment of cancer: 2020–present
2个月前
已完结
Antiviral actions of natural compounds against dengue virus RNA dependent RNA polymerase: insights from molecular dynamics and Gibbs free energy landscape
3个月前
已完结
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