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Modulating Antibody–Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification
1天前
已完结
Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody–Drug Conjugates
1天前
已完结
CLDN18.2–targeting antibody–drug conjugate IBI343 in advanced gastric or gastroesophageal junction adenocarcinoma: a phase 1 trial
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A Traceless Site‐Specific Conjugation on Native Antibodies Enables Efficient One‐Step Payload Assembly
1个月前
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Proof of site-specificity of antibody-drug conjugates produced by chemical conjugation technology: AJICAP first generation
1个月前
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AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Selective Antibody–Drug Conjugate Synthesis
2个月前
已完结
Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
3个月前
已完结
Simple and versatile high-performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of camptothecin anticancer drugs
4个月前
已完结
Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins
4个月前
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Trastuzumab rezetecan, a HER2-directed antibody–drug conjugate, in patients with advanced HER2-mutant non-small-cell lung cancer (HORIZON-Lung): phase 2 results from a multicentre, single-arm study
4个月前
已完结
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