Lv11
32 积分 2023-12-05 加入
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
11小时前
已完结
Finding a needle in the haystack: ADME and pharmacokinetics/pharmacodynamics characterization and optimization toward orally available bifunctional protein degraders
5天前
已完结
Structure, function and pharmacology of human itch receptor complexes
1个月前
已完结
Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
1个月前
已完结
Discovery of Novel Rigid STING PROTAC Degraders as Potential Therapeutics for Acute Kidney Injury
1个月前
已完结
Discovery of autophagy-tethering compounds as potent NLRP3 degraders for IBD Immunotherapy
1个月前
已完结
Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis
1个月前
已完结
Discovery of novel IRAK-4 inhibitors through multi-level virtual screening pipeline and molecular dynamics simulations
1个月前
已关闭
Benchmarking Methods for PROTAC Ternary Complex Structure Prediction
1个月前
已完结
Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors
1个月前
已完结
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