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56 积分 2025-09-23 加入
RATIONAL DRUG DESIGN OF POTENT V600E-BRAF KINASE INHIBITORS THROUGH MOLECULAR DOCKING SIMULATION
1个月前
已完结
In Silico Identification of Novel and Potent Inhibitors Against Mutant BRAF (V600E), MD Simulations, Free Energy Calculations, and Experimental Determination of Binding Affinity
1个月前
已完结
The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells
1个月前
已完结
Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process
1个月前
已完结
Design, synthesis, and biological evaluation of novel probe-quality EGFR degraders targeting wild-type and Del19 mutation
3个月前
已关闭
Oxygen-atom replacement in non-strained cyclic ethers
4个月前
已完结
Discovery of potent CRBN-recruiting epidermal growth factor receptor (EGFR) degraders in vitro
4个月前
已完结
Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment
4个月前
已完结
Design and Synthesis of 2‐Aminopyrazolpyrimidopyridone Derivatives as RETV804M and RETG810C Kinase Inhibitors
4个月前
已完结
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