Lv1
20 积分 2025-09-23 加入
Oxygen-atom replacement in non-strained cyclic ethers
29天前
已完结
Discovery of potent CRBN-recruiting epidermal growth factor receptor (EGFR) degraders in vitro
1个月前
已完结
Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment
1个月前
已完结
Design and Synthesis of 2‐Aminopyrazolpyrimidopyridone Derivatives as RETV804M and RETG810C Kinase Inhibitors
1个月前
已完结
Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC)
1个月前
已完结
Synthesis and degradation effect of PROTACs targeting EGFR triple mutants
1个月前
已关闭
HBE‐843, a Novel, Potent, and Selective EGFR Targeting PROTAC for the Treatment of Non‐Small‐Cell Lung Cancer
1个月前
已完结
A pomalidomide-based gefitinib PROTAC degrader effectively inhibits lung cancer progression in EGFR-TKIs-acquired resistant models by targeting EGFR degradation and ETFA-mediated ATP generation
4个月前
已完结
HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations
4个月前
已完结
Exploring molecular interactions of potential inhibitors against the spleen tyrosine kinase implicated in autoimmune disorders via virtual screening and molecular dynamics simulations
7个月前
已完结
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