Lv11
38 积分 2023-11-13 加入
Design, synthesis and structure–activity relationship of indolylindazoles as potent and selective covalent inhibitors of interleukin-2 inducible T-cell kinase (ITK)
1小时前
已完结
Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
2个月前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
2个月前
已完结
Discovery of APH02174 as a Highly Selective and Orally Bioavailable IRAK4 Degrader for the Treatment of Inflammatory Diseases
4个月前
已完结
Selective Inhibition of STAT3 with Respect to STAT1: Insights from Molecular Dynamics and Ensemble Docking Simulations
5个月前
已完结
Discovery of Potential Natural STAT3 Inhibitors: An in silico Molecular Docking and Molecular Dynamics Study
5个月前
已完结
Glide WS: Methodology and Initial Assessment of Performance for Docking Accuracy and Virtual Screening
5个月前
已完结
Glide WS: Methodology and Initial Assessment of Performance for Docking Accuracy and Virtual Screening
5个月前
已完结
AI-Driven Efficient De Novo design of GLP-1RAs with Extended Half-Life and Enhanced Efficacy
6个月前
已完结
SIRT1 activation by Taurine: in vitro evaluation, molecular docking and molecular dynamics simulation studies
10个月前
已完结
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