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crush
Lv1
1
30 积分
2023-11-13 加入
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Discovery of a Potent FLT3 Inhibitor (LT-850-166) with the Capacity of Overcoming a Variety of FLT3 Mutations
5小时前
待确认
Discovery of APH02174 as a Highly Selective and Orally Bioavailable IRAK4 Degrader for the Treatment of Inflammatory Diseases
3天前
已完结
Computational insights of deucravacitinib’s selectivity for TYK2 pseudokinase vs. JAK kinase domain via molecular modeling studies
2个月前
已完结
First de novo deuterated drug poised for approval
5个月前
已完结
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action
7个月前
已完结
Drug discovery targeting Nav1.8: Structural insights and therapeutic potential
7个月前
已完结
Conformational landscapes of artificial peptides predicted by various force fields: are we ready to simulate β-amino acids?
8个月前
已关闭
Discovery of a novel series of pyridone amides as NaV1.8 inhibitors
9个月前
已完结
Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability
11个月前
已完结
Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability
11个月前
已完结
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