Lv72
4490 积分 2024-03-01 加入
Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer
7天前
已完结
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders
14天前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
1个月前
已完结
Targeting cancer with small molecule pan-KRAS degraders
1个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
1个月前
已完结
TMEM175: A lysosomal ion channel associated with neurological diseases
2个月前
已完结
Mechanism and therapeutic targets of the involvement of a novel lysosomal proton channel TMEM175 in Parkinson's disease
2个月前
已完结
First-in-Class Clinically Investigated Oral Factor D Inhibitors for the Treatment of Complement-Mediated Diseases
3个月前
已完结
AI-assisted delivery of novel covalent WRN inhibitors from a non-covalent fragment screen
3个月前
已完结
Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties
3个月前
已完结
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