Lv11
66 积分 2024-09-12 加入
Discovery and preclinical evaluations of drug candidate DA-0157 capable of overcoming EGFR drug-resistant mutation C797S and EGFR/ALK co-mutations
9个月前
已完结
Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
10个月前
已完结
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
10个月前
已完结
Structural Mechanism and Inhibitors Targeting EGFR Exon 20 Insertion (Ex20ins) Mutations
10个月前
已完结
Optimization of Potent, Efficacious, Selective and Blood–Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations
10个月前
已完结
Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib
10个月前
已完结
Discovery of a Novel Potent EGFR Inhibitor Against EGFR Activating Mutations and On-Target Resistance in NSCLC
10个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation
10个月前
已完结
Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC
10个月前
已完结
Novel EGFR Inhibitors against Resistant L858R/T790M/C797S Mutant for Intervention of Non-Small Cell Lung Cancer
11个月前
已完结
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