Lv11
50 积分 2024-05-08 加入
Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
1小时前
已完结
Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance
1小时前
已完结
Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
2个月前
已完结
High-Throughput Experimentation Reveals Scope and Limitations of Selective Phosphine Reductants and Enables One-Pot mAb Reduction/Conjugation
4个月前
已完结
The antibody–drug conjugate landscape
7个月前
已完结
The Journey of Antibody–Drug Conjugates: Lessons Learned from 40 Years of Development
8个月前
已完结
Topoisomerase I-Mediated DNA Relaxation as a Tool to Study Intercalation of Small Molecules into Supercoiled DNA
11个月前
已关闭
Trastuzumab deruxtecan in patients with HER2-positive advanced colorectal cancer (DESTINY-CRC02): primary results from a multicentre, randomised, phase 2 trial
1年前
已完结
Recent advances in the tumor‐penetrating peptide internalizing RGD for cancer treatment and diagnosis
1年前
已完结
Structure–Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity
1年前
已完结
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