Lv1
22 积分 2024-02-20 加入
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFRL858R/T790M/ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers
8小时前
已完结
Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases
8小时前
已完结
The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies
3天前
已完结
Dendritic cells in vaccination therapies of malignant diseases
2个月前
已完结
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
2个月前
已完结
Amplifying antigen-induced cellular responses with proximity labelling
2个月前
已完结
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling
2个月前
已完结
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients
5个月前
已完结
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR
5个月前
已完结
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
5个月前
已完结
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