Lv4
510 积分 2022-11-14 加入
Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-d]pyrimidine Analogues Bearing Deuterated Methylene Linkers as Potent KRASG12D Inhibitors
1年前
已完结
Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2)
1年前
已完结
Current kinase inhibitors cover a tiny fraction of fragment space
1年前
已完结
Second-Generation AUTACs for Targeted Autophagic Degradation
1年前
已完结
Synthesis and in vitro anticancer activity of some 2-oxindoline derivatives as potential CDK2 inhibitors
1年前
已完结
Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity
1年前
已完结
Delivering on the promise of protein degraders
1年前
已完结
3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders
1年前
已完结
Synthesis and biological evaluation of novel pteridin-7(8H)-one derivatives as potent CDK2 inhibitors
1年前
已完结
Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design
1年前
已完结
皖公网安备34019202002308
