Lv31
234 积分 2023-11-16 加入
Network-driven identification of indisulam neo-substrates for targeted protein degradation
6小时前
已完结
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
6天前
已完结
Single-Atom Modification Enables Reversal of Degradation Selectivity between NSD2 and GSPT1
9天前
已完结
Discovery of molecular glue degrader for treatment of IMiDs-resistant multiple myeloma based on GLUT-mediated tumor targeting strategy
11天前
已完结
Discovery of a Small-Molecule Inhibitor Targeting the Androgen Receptor N-Terminal Domain for Castration-Resistant Prostate Cancer
1个月前
已完结
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2
1个月前
已完结
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
1个月前
已完结
An OpenMM-BasedML/MM–MMGBSA Workflow for End-pointProtein–Ligand Binding Energy Ranking
1个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
3个月前
已完结
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
3个月前
已完结
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