Lv4
650 积分 2022-11-25 加入
Discovery of Thieno[3,2-d]pyrimidine derivatives as potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) kinase
3个月前
已完结
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
3个月前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
5个月前
已完结
D3S-001 in advanced solid tumors with KRASG12C mutations: a phase 1 trial
7个月前
已完结
Molecular Determinants of Clinical Outcomes In a Real-World Diffuse Large B-cell Lymphoma Population
7个月前
已完结
Targeting MALT1 for the treatment of diffuse large B-cell lymphoma
7个月前
已完结
MALT1 as a promising target to treat lymphoma and other diseases related to MALT1 anomalies
7个月前
已完结
Development of Potent MALT1 Inhibitors Featuring a Novel “2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one” Scaffold for the Treatment of B Cell Lymphoma
7个月前
已完结
Sgr-1505 Is a Potent MALT1 Protease Inhibitor with a Potential Best-in-Class Profile
7个月前
已完结
The paracaspase MALT1 is a downstream target of Smad3 and potentiates the crosstalk between TGF-β and NF-kB signaling pathways in cancer cells
7个月前
已完结
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