Lv2
130 积分 2024-08-23 加入
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases
6天前
已完结
Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2
6天前
已完结
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases
7天前
已完结
NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly
14天前
已完结
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
14天前
已完结
NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
19天前
已完结
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127
1个月前
已完结
Bispecific therapeutics: a state-of-the-art review on the combination of immune checkpoint inhibition with costimulatory and non-checkpoint targeted therapy
1个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
1个月前
已完结
An evaluation of zanidatamab, a novel, anti-HER2 biparatopic antibody, for the treatment of biliary tract cancer
2个月前
已完结
Osimertinib and stereotactic radiosurgery for brain metastases in EGFR mutated lung cancer - The STARLET joint analysis of OUTRUN and LUOSICNS randomised trials
1个月前
已采纳
Osimertinib and stereotactic radiosurgery for brain metastases in EGFR mutated lung cancer - The STARLET joint analysis of OUTRUN and LUOSICNS randomised trials
1个月前
已采纳
Osimertinib and stereotactic radiosurgery for brain metastases in EGFR mutated lung cancer - The STARLET joint analysis of OUTRUN and LUOSICNS randomised trials
1个月前
已采纳
Osimertinib and stereotactic radiosurgery for brain metastases in EGFR mutated lung cancer - The STARLET joint analysis of OUTRUN and LUOSICNS randomised trials
1个月前
已采纳