Lv5
1054 积分 2024-10-15 加入
Leveraging Bidirectional Nature of Allostery To Inhibit Protein–Protein Interactions (PPIs): A Case Study of PCSK9–LDLR Interaction
12小时前
已完结
Mixed-Solvent Molecular Dynamics Simulation Reveals a Druggable Allosteric Pocket in the PCSK9 C-Terminal Domain
1天前
已完结
Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB‐78485 inhibitor
1个月前
已完结
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety
1个月前
已完结
Target identification and assessment in the era of AI
2个月前
已完结
Characterization of Heterocyclic Rings through Quantum Chemical Topology
2个月前
已完结
Mitigating Heterocycle Metabolism in Drug Discovery
3个月前
已完结
An Internal Sulfur–Lone Pair Interaction Enabled the Discovery of Potent and Sub‐Family Selective PKMYT1 Inhibitors
3个月前
已完结
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition
3个月前
已完结
In-Depth Cerebrospinal Fluid Quantitative Proteome and Deglycoproteome Analysis: Presenting a Comprehensive Picture of Pathways and Processes Affected by Multiple Sclerosis
4个月前
已完结
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