Lv11
94 积分 2022-07-02 加入
Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors
1小时前
待确认
CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival
2小时前
已完结
Inhibition of the Cyclin K‐CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer
2小时前
待确认
PAF1C-mediated activation of CDK12/13 kinase activity is critical for CTD phosphorylation and transcript elongation
3小时前
已完结
Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer
27天前
已完结
Discovery of Novel Imidazo[1,2-B]Pyridazine Derivatives as Potent Covalent Inhibitors of Cdk12/13
1个月前
已完结
CDK12/13 Inhibitor SR-4835 Is Active in Triple-Negative Breast Cancer
1个月前
已完结
Advances in Structural Types and Pharmacochemistry of CDK12 Inhibitors
1个月前
已完结
Discovery of ZLC491 as a Potent, Selective, and Orally Bioavailable CDK12/13 PROTAC Degrader
1个月前
已完结
Physiological and pathological roles of the transcriptional kinases CDK12 and CDK13 in the central nervous system
1个月前
已完结
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