Lv6
1772 积分 2022-07-14 加入
Scaffold hopping–directed design and discovery of N1-substituted aminopyrimidine–indole derivatives as FAK inhibitors with anti-pancreatic cancer activity
16小时前
已关闭
https://pubs.acs.org/doi/10.1021/acs.orglett.6c01786
3天前
已完结
Discovery of BBI-355, a Potent, Selective, and Orally Available Checkpoint Kinase 1 Inhibitor for the Treatment of Extrachromosomal DNA Oncogene-Amplified Cancers
4天前
已关闭
Protein Abundance of Hydrolytic Drug Metabolizing Enzymes in Different Tissues and across Species
25天前
已完结
Pep2MARS: Automated Cyclic Peptide Parameterization for Molecular Dynamics and Compound Design
1个月前
已完结
QSAR Analysis and Molecular Docking Simulation of Suggested Peptidomimetic NS3 Protease Inhibitors
1个月前
已完结
Architecture and activation of single-pass transmembrane receptor guanylyl cyclase
1个月前
已完结
Design, synthesis, and biological evaluation of 1H-1,2,4-triazole-3-carboxamides as apelin receptor agonists
2个月前
已完结
Accurate 3D Structure Prediction of Small Cyclic Peptides Containing Non-Canonical Amino Acid Residues Using an All-Atom Diffusion Model with Stereogenic Implementation
2个月前
已完结
Target identification and assessment in the era of AI
2个月前
已完结
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