Lv5
1340 积分 2025-05-14 加入
Plasma Protein Binding Refinement of the Extended Clearance Classification System: Subclasses for Predicting Hepatic Uptake or Renal Clearance for Classes 1B and 3B
2天前
求助中
Prediction of Drug Clearance from Enzyme and Transporter Kinetics
3天前
已完结
Hepatic Clearance Predictions from In Vitro–In Vivo Extrapolation and the Biopharmaceutics Drug Disposition Classification System
6天前
已完结
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species
6天前
已完结
In silico approach shows good predictability for free fraction in plasma and volume of distribution in human for drugs subjected to lysosomal trapping
7天前
已关闭
Utility of Hepatocytes in Predicting Drug Metabolism: Comparison of Hepatic Intrinsic Clearance in Rats and Humans in Vivo and in Vitro
8天前
已完结
Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes
8天前
已完结
In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes
8天前
已完结
Furo[2,3- f ]quinazolin-7(6 H )-one Derivatives as Potent, Selective, and Orally Bioavailable MAT2A Inhibitors for MTAP-Deficient Cancer Therapy
9天前
已完结