Lv414
530 积分 2025-03-13 加入
Photocatalytic Strategy to Realize N-Debenzylation via Aerobic Oxidation Catalyzed by 4CzIPN
12天前
已完结
Intercepting the Downstream of the Estrogen Receptor Signaling Pathway: Discovery of a Potent and Efficient SRC-3 PROTAC Degrader for Overcoming Endocrine Resistance Breast Cancer
16天前
已完结
Discovery of a Proteolysis-Targeting Chimera Degrader of JAK2 as a Potential Therapeutic Agent for JAK2-Mediated Myeloproliferative Neoplasms
16天前
已关闭
RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345
16天前
已关闭
RORγt inhibitors in clinical development for the treatment of autoimmune diseases: challenges and opportunities
18天前
已完结
Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
24天前
已完结
Discovery of a New and Selective HPK1 PROTAC for Enhancing Tumor Immunotherapy through Eliminating GLK Degradation
30天前
已完结
Deucravacitinib: The First FDA-Approved Oral TYK2 Inhibitor for Moderate to Severe Plaque Psoriasis
1个月前
已完结
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712
1个月前
已完结
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
1个月前
已完结
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