Lv6
2940 积分 2025-03-13 加入
Next-generation strategies for PROTAC formulation: mechanistic insights and advanced formulation technologies
14小时前
已完结
Applications of covalent chemistry in targeted protein degradation
8天前
已完结
Covalent Proximity Inducers
8天前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
16天前
已完结
The Discovery of TNG456: A Highly Potent, Selective, Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers
1个月前
已完结
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation
1个月前
已完结
Early Process Development of a Heterobifunctional Protein Degrader
2个月前
已完结
Design, Synthesis, and Identification of an Orally Bioavailable Small-Molecule HBsAg Production Inhibitor with High Hepatoselectivity and Reduced Neurotoxic Potential
2个月前
已完结
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist
2个月前
已完结
Discovery of FLT3-ITD Inhibitor Clifutinib: A Novel Biphenylacetylene Urea Derivative in Clinical Trials for the Treatment of Relapsed/Refractory FLT3-ITD+ Acute Myeloid Leukemia
2个月前
已完结
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