cocode
Lv38
220 积分
2023-09-25 加入
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Design, Synthesis, and Structure–Activity Relationship of Novel Pyridazinone-Based PARP7/HDACs Dual Inhibitors for Elucidating the Relationship between Antitumor Immunity and HDACs Inhibition
2天前
已完结
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Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer
6天前
已完结
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Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient Tumors
12天前
已完结
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Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors
13天前
已完结
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Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target
13天前
已完结
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Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors
13天前
已完结
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How Well Does the Extended Linear Interaction Energy Method Perform in Accurate Binding Free Energy Calculations?
19天前
已完结
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Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach
21天前
已完结
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Comparing the Performance of Different AMBER Protein Forcefields, Partial Charge Assignments, and Water Models for Absolute Binding Free Energy Calculations
24天前
已完结
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Dual Nicotinamide Phosphoribosyltransferase (NAMPT) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors for the Treatment of Drug-Resistant Nonsmall-Cell Lung Cancer
28天前
已完结