Lv6
2550 积分 2024-01-09 加入
Selective and Potent Molecular Glue Degraders for NIMA‐related Kinase 7
2天前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
29天前
已完结
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers
1个月前
已完结
Discovery of the Clinical Candidate YY2201 as a Highly Potent and Selective ATR Inhibitor
1个月前
已完结
Design of Potent Menin–KMT2A Interaction Inhibitors with Improved In Vitro ADME Properties and Reduced hERG Affinity
2个月前
已完结
Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure–Activity Relationships Insights and Evolution Prospects
2个月前
已完结
Discovery of JAB-3312, a Potent SHP2 Allosteric Inhibitor for Cancer Treatment
2个月前
已完结
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor
3个月前
已完结
In Silico Enabled Discovery of KAI-11101, a Preclinical DLK Inhibitor for the Treatment of Neurodegenerative Disease and Neuronal Injury
4个月前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
4个月前
已完结
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