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244 积分 2024-08-26 加入
Applications of Bioisosteres in the Design of Biologically Active Compounds
5小时前
已完结
Acyl Glucuronide and Coenzyme A Thioester Metabolites of Carboxylic Acid-Containing Drug Molecules: Layering Chemistry with Reactive Metabolism and Toxicology
6天前
已完结
Designing Chromane Derivatives as α2A-Adrenoceptor Selective Agonists via Conformation Constraint
11天前
已完结
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+ Acute Myeloid Leukemia (AML)
13天前
已完结
Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery
13天前
已完结
Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat
19天前
已完结
Dual inhibition strategy addressing hyperuricemia and oxidative stress: design, biological evaluation and stability studies of febuxostat-probenecid mutual prodrug
26天前
已完结
A Combination of Pharmacophore Generation, Ligand-based Virtual Screening, Atom-based 3D-QSAR, and Molecular Docking Studies on Febuxostat-based Amides Analogues as Anti-inflammatory Agents
27天前
已完结
UDP-glucuronosyltransferases: Structure, Function and Drug Design Studies
1个月前
已完结
Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout
1个月前
已完结
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