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10 积分 2026-03-19 加入
Pretargeted PROTAC Strategy Enables Precise Tumor Target Degradation via Self-Assembling Peptides
17天前
已完结
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
17天前
已完结
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
17天前
已完结
Sulfatase-Induced In Situ Formulation of Antineoplastic Supra-PROTACs
21天前
已完结
Development of Phenyl‐substituted Isoindolinone‐ and Benzimidazole‐type Cereblon Ligands for Targeted Protein Degradation
29天前
已完结
Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands
29天前
已完结
Rifamycin O as a novel CRBN ligand for targeted degradation of IKZF1/3 proteins in hematopoietic malignancies
29天前
已完结
Direct regioselective C-3 halogenation of pyridines
1个月前
已完结
NAMPT-targeted para-ureidobenzylamine derivatives: Design, synthesis, and antitumor evaluation in gastrointestinal cancers
1个月前
已完结
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