Lv3
310 积分 2023-03-18 加入
Phosphodiesterase 4B (PDE4B) inhibitors and their applications in recent years (2014 to early 2025)
6小时前
已完结
Discovery of an Indole-Based p53-Y220C Reactivator with In Vivo Antitumor Activity via Structure-Guided Design
9小时前
已完结
Structure-Based Design and Optimization of Novel PHGDH Inhibitors for Overcoming Erlotinib-Resistant Lung Cancer
9小时前
已完结
Design, Synthesis, and Evaluation of Dihydropyrimidine Derivatives as Selective PDE1 Inhibitors for the Treatment of Liver Fibrosis
1天前
已完结
Nerandomilast: First Approval
20天前
已完结
Discovery of Peripherally Restricted Indazole-Based Phosphodiesterase 4B Inhibitors Targeting the C-terminal Regulatory Helix for Treating Acute Lung Injury
1个月前
已完结
Bifunctional LYTAC Mediates Hepatocytes-Hepatic Stellate Cells Crosstalk by Regulating 5-HT 2A Receptor Degradation and Antagonism to Synergistically Ameliorate Hepatic Fibrosis
1个月前
已完结
Discovery of Highly Potent, Selective, and Liver-Targeted THR-β Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis
1个月前
已完结
Resmetirom: the first approved therapy for treating metabolic dysfunction associated steatohepatitis
1个月前
已完结
Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice
1个月前
已完结
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