Lv3
342 积分 2023-06-12 加入
Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2-Ethynylthiazole-4-carboxamide as Electrophilic Warhead
8个月前
已完结
Innovative Medicinal Chemistry Strategies for Improving Target Binding Kinetics in Drug Discovery
8个月前
已完结
OSMAC strategy integrated with molecular networking discovery peniciacetals A−I, nine new meroterpenoids from the mangrove-derived fungus Penicillium sp. HLLG-122
8个月前
已完结
Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells
8个月前
已完结
A Refined Adaptive Laboratory Evolution Strategy With Biosensor‐Assisted Selection Resolves the Tolerance–Efficiency Trade‐Off in Toxic Chemical Biosynthesis
10个月前
已关闭
Design, Synthesis, and Biological Evaluation of Quinoline-Based Hydroxamic Acid Derivatives as Dual DNMT and HDAC Inhibitors with Potent Anti-Breast Cancer Activity
10个月前
已完结
Site-selective structural modification of toosendanin enables one-step synthesis of 12-hydroxyamoorastatin: A natural tautomeric antitumor lead with low toxicity
10个月前
已完结
Development of a Scalable Electrophilic Amination Protocol for the Multi-kg Production of 5-Methyl-2-pyridinesulfonamide: A Regulatory Starting Material of Endothelin Receptor Antagonist Clazosentan
11个月前
已完结
Progress in Synthesis and Antagonistic Activities towards PAFR and GlyR of Ginkgolide Derivatives and Analogs
11个月前
已关闭
Ginkgolides and Glycine Receptors: A Structure–Activity Relationship Study
11个月前
已完结
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