Lv11
20 积分 2025-04-27 加入
Discovery of potent NAMPT-Targeting PROTACs using FK866 as the warhead
3天前
已完结
Design, Synthesis, and Biological Evaluation of Androgen Receptor (AR) Antagonist-Heat Shock Protein 90 (Hsp90) Inhibitor Conjugates for Targeted Therapy of Castration-Resistant Prostate Cancer
3天前
已完结
Discovery of Novel SHP2 ATTEC Degraders against Pancreatic Ductal Adenocarcinoma Harboring KRAS(G12D) Mutations
3天前
已完结
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
4天前
已完结
Discovery of autophagy-tethering compounds as potent NLRP3 degraders for IBD Immunotherapy
4天前
已完结
Autophagy-Activating Nanoautophagosome-Tethering Compounds for Targeted Protein Degradation Specifically in Tumor Cells
4天前
已完结
Autophagy receptor-inspired chimeras: a novel approach to facilitate the removal of protein aggregates and organelle by autophagy degradation
5天前
已完结
Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides
5天前
已完结
Second-Generation AUTACs for Targeted Autophagic Degradation
5天前
已完结
Mechanisms and therapeutic strategies for NLRP3 degradation via post-translational modifications in ubiquitin-proteasome and autophagy lysosomal pathway
5天前
已完结
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