Lv53
846 积分 2024-03-03 加入
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
2天前
已完结
Discovery of Carbodiimide Warheads to Selectively and Covalently Target Aspartic Acid in KRASG12D
2天前
已完结
Design, Synthesis and Biological Evaluation of 7-(1-Methyl-1H-indole-3-yl)-5H-pyrrolo[2,3-b]pyrazine Derivatives as Novel Covalent pan-FGFR Inhibitors to Overcome Clinical Resistance
2个月前
已完结
Lysine‐targeting, Covalent Inhibitors of Bromodomain BD1 of BET Proteins in Live Cells and Animals
5个月前
已完结
Covalent Recruitment of NEDD4 for Targeted Protein Degradation: Rational Design of Small Molecular Degraders
5个月前
已完结
Developing Potent and Selective Anticancer Therapy through Chemical Approaches and the Combination of Cationic Amphipathic Oncolytic Peptides
6个月前
已完结
Substituted Isobutyrophenones
6个月前
已完结
Triazination/IEDDA Cascade Modular Strategy Installing Pyridines/Pyrimidines onto Tyrosine Enables Peptide Screening and Optimization
7个月前
已完结
Acylation of phenols to phenolic esters with organic salts
8个月前
已完结
PKS and NRPS release mechanisms
9个月前
已完结