Lv4
448 积分 2022-12-28 加入
Diethenyl Sulfoximine (DESI) as an Irreversible Lysine‐Targeting Warhead Enables the Design of Covalent Allosteric EGFR Inhibitor
4个月前
已完结
Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2
4个月前
已完结
Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4
4个月前
已完结
A highly selective and orally bioavailable casein kinase 1 alpha degrader through p53 signaling pathway targets B-cell lymphoma cells
4个月前
已完结
JMC14: a novel dual PI3Kδ/CSF1R inhibitor with potent antitumor activity in hematological and solid tumors
4个月前
已完结
Enzyme‐Activated Orthogonal Proteolysis Chimeras for Tumor Microenvironment‐Responsive Immunomodulation
4个月前
已完结
Enzyme‐Activated Orthogonal Proteolysis Chimeras for Tumor Microenvironment‐Responsive Immunomodulation
4个月前
已完结
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway
4个月前
已完结
Pharmacological inhibition of PSPH reduces serine levels and epileptic seizures
4个月前
已完结
Design, synthesis, and biological evaluation of novel PI3Kδ/HDAC6 dual inhibitors for the treatment of non-Hodgkin’s lymphoma
4个月前
已关闭
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