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58 积分
2025-08-26 加入
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Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects
1天前
待确认
Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy
14天前
已完结
High-resolution structural information of membrane-bound α-synuclein provides insight into the MoA of the anti-Parkinson drug UCB0599
15天前
已完结
Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades
15天前
已完结
Matters arising: In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson’s disease
15天前
已完结
Asymmetric catalysis with a chiral-at-osmium complex
17天前
已完结
Molecular cloning, characterization and developmental expression of porcine β-synuclein
17天前
已完结
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors
18天前
已完结
Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation
18天前
已完结
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson’s disease
24天前
已完结
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