Lv43
430 积分 2023-04-18 加入
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy
1天前
已完结
Ketone reduction drives major circulating metabolites of GDC-8264 in humans
2天前
求助中
Evaluation of Oral PROTAC Guidelines: Efflux Ratio Outweighs Chameleonicity Descriptors
3天前
已完结
Reducing PD-L1 Expression by Degraders and Downregulators as a Novel Strategy to Target the PD-1/PD-L1 Pathway
7天前
已完结
New horizons in the mechanisms and therapeutic strategies for PD-L1 protein degradation in cancer
7天前
已完结
Discovery of a Potent RXRγ Degrader WCF-598 for the Treatment of Castration-Resistant Prostate Cancer
9天前
已完结
Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity
12天前
已完结
Design, synthesis, and evaluation of PD-L1 degraders to enhance T cell killing activity against melanoma
12天前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
12天前
已完结
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
12天前
已完结
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