Lv34
330 积分 2023-04-18 加入
Discovery of Rigid Linker-Based IRAK4 PROTACs with Improved Metabolic Stability for the Treatment of Inflammatory Diseases
2天前
已完结
A Perspective on the Strategic Application of Deconstruction–Reconstruction in Drug Discovery
9天前
已完结
Targeted protein degradation for cancer therapy
9天前
已完结
Advancing targeted protein degradation for cancer therapy
10天前
已完结
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library Screen
10天前
已完结
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
13天前
已完结
Designing Macrocyclic Kinase Inhibitors Using Macrocycle Scaffold Hopping with Reinforced Learning (Macro-Hop)
13天前
已完结
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
13天前
已完结
Discovery of Highly Selective and Potent Macrocyclic JAK2 Inhibitors for the Treatment of MPNs
13天前
已完结
Insights on Volume of Distribution of Acids
15天前
已完结
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