Lv3
370 积分 2023-04-18 加入
Selective CDK2 Degradation via Noncanonical Recruitment
4天前
已完结
PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation
5天前
已完结
Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists
6天前
已完结
Discovery of a Selective Histone Deacetylase 6 Degrader (HDAC6 PROTAC) with a Short and Rigid Linker Demonstrating Sustained Knockdown of HDAC6 In Vivo
7天前
已完结
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
9天前
已完结
Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia
10天前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
10天前
已完结
Glycoengineered Host-Guest Nanoparticles Potentiate Alzheimer’s Disease Therapy via Lesion-Specific Modulation of Tau Pathology
10天前
已完结
Androgen receptor splice variant 7 (AR-V7) in castration-resistant prostate cancer: Molecular mechanisms and therapeutic strategies
11天前
已完结
Pseudoprolines as stereoelectronically tunable proline isosteres
13天前
已完结
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