Lv45
570 积分 2023-04-18 加入
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design
1天前
待确认
Discovery of Histone Deacetylase 8-Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies
3天前
已完结
Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies
3天前
已完结
Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4
5天前
已完结
Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells
6天前
已完结
Deep Modeling of Gain‐of‐Function Mutations on Androgen Receptor
7天前
已完结
Property-Based Prediction Uncovers Intestinal Excretion as an Elimination Route of Small-Molecule Drugs
7天前
已完结
The Discovery of GS-1291269: A Neutral Ketohexokinase (KHK) Inhibitor with an Unusual Thietane Amine Functional Group
14天前
已完结
Discovery of a Small-Molecule Inhibitor Targeting the Androgen Receptor N-Terminal Domain for Castration-Resistant Prostate Cancer
15天前
已完结
RETRACTED: SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain
15天前
已完结