Lv2
176 积分 2023-08-04 加入
Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds
12小时前
待确认
Discovery and characterization of YSA64, a RBM39 degrader with in vivo efficacy and potent cellular activity in pediatric Ewing sarcoma A673
13天前
已完结
Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer
1个月前
已完结
Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer
1个月前
已完结
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer
1个月前
已完结
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
2个月前
已完结
Discovery ofaNovel Series of iso -Indolinone-Based Glutarimidesas Highly Efficacious and SelectiveIKZF2 Molecular Glue Degraders
2个月前
已完结
Mechanism of Action and Novel IMiD-Based Compounds and Combinations in Multiple Myeloma
2个月前
已完结
Discovery of a Novel Series of iso-Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders
2个月前
已完结
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
2个月前
已完结
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