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560 积分
2023-04-18 加入
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Discovery of small-molecule modulators of ppGalNAc-T2 targeting the metastable states during its loop-closing process
12天前
已完结
Discovery of novel thiazolylhydrazone derivatives as potent anti-cancer agents inducing ferroptosis via direct NRF2 inhibition
18天前
已完结
Novel β-carboline derivatives show promise as dual-target inhibitors of DNA and TOP2A for the treatment of triple negative breast cancer
25天前
已完结
Design, Optimization, and Biological Evaluation of a Novel Quinoline-Based POLRMT Inhibitor for Prostate Cancer Therapy
1个月前
已完结
Design, synthesis and biological evaluation anti-angiogenesis study of a novel platelet-derived growth factor receptor-α (PDGFR-α) inhibitors based on 4-anilinoquinoline and 4-anilinoquinazoline scaffolds
1个月前
已关闭
Identification of Novel Target DCTPP1 for Colorectal Cancer Therapy with the Natural Small‐molecule Inhibitors Regulating Metabolic Reprogramming
10个月前
已完结
Discovery of Dehydrogenated Imipridone Derivatives as Activators of Human Caseinolytic Protease P
11个月前
已完结
Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient Tumors
1年前
已完结
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer
1年前
已完结
Discovery of Novel Dual Inhibitors Targeting Mutant IDH1 and NAMPT for the Treatment of Glioma with IDH1Mutation
1年前
已完结
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