Lv11
50 积分 2024-10-20 加入
Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral Sarcothelia edmondsoni
37分钟前
已完结
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors
1年前
已完结
The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics
1年前
已关闭
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design
1年前
已完结
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors
1年前
已完结
Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores
1年前
已完结
Drug discovery targeting Nav1.8: Structural insights and therapeutic potential
1年前
已完结