Lv31
220 积分 2024-11-07 加入
Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation
1小时前
已完结
Regulation of STAT signaling by acetylation
9天前
已完结
Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation
9天前
已完结
Discovery of Dual BCL-xL/BCL-w Degraders by Exploiting the Bis(sulfonyl)benzene Ring of ABT-263 as a Linkage Vector
11天前
已完结
Metal–N-Heterocyclic Carbene Complexes in Buchwald–Hartwig Amination Reactions
1个月前
已完结
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
2个月前
已完结
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
3个月前
已完结
Probing the E3 Ligase Adapter Cereblon with Chemical Biology
4个月前
已完结
Targeted Protein Degradation: From Basic Science to Therapeutic Applications
4个月前
已完结
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
4个月前
已完结
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