Lv23
200 积分 2024-11-07 加入
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
8天前
已完结
Probing the E3 Ligase Adapter Cereblon with Chemical Biology
1个月前
已完结
Targeted Protein Degradation: From Basic Science to Therapeutic Applications
1个月前
已完结
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
1个月前
已完结
The Emergence of Oligonucleotide Building Blocks in the Multispecific Proximity-Inducing Drug Toolbox of Destruction
2个月前
已完结
The Potential of PARP Inhibitors as Antitumor Drugs and the Perspective of Molecular Design
2个月前
已完结
Journey of PROTAC: From Bench to Clinical Trial and Beyond
2个月前
已完结
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
2个月前
已完结
Research Advances in Chaperone-Mediated Autophagy (CMA) and CMA-Based Protein Degraders
2个月前
已完结
Analyzing the Linker Structure of PROTACs throughout the Induction Process: Computational Insights
2个月前
已完结
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