Lv7
5006 积分 2021-02-11 加入
Discovery of novel covalent agonists for p53 Y220C through synergistic strategy combining covalent binding and scaffold hopping
26天前
已完结
In vivo tumor growth of high-grade serous ovarian cancer cell lines
28天前
已完结
Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab
2个月前
已完结
Bioanalysis for PK for antibody drug conjugates using ligand binding assay–challenges and bioanalytical strategies
2个月前
已完结
Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C–Mutated Tumors
2个月前
已完结
Construction of Small‐Molecule Deubiquitinase‐Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo
2个月前
已完结
Systemic delivery of cadherin 17–specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases
3个月前
已完结
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues
3个月前
已完结
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues
3个月前
已完结
Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis
3个月前
已完结