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860 积分 2023-02-03 加入
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Degraders for Treating Inflammatory Diseases: Advances and Prospects
15天前
已完结
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation
15天前
已完结
A Interacting Model: How TRIM21 Orchestrates with Proteins in Intracellular Immunity
23天前
已完结
An Efficient Approach Toward Drugging Undruggable Targets
1个月前
已完结
Structural and molecular insights of protein tyrosine phosphatase 1B (PTP1B) and its inhibitors as anti-diabetic agents
2个月前
已完结
Small-molecule LRRK2 inhibitors for PD therapy: Current achievements and future perspectives
2个月前
已完结
Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex
2个月前
已完结
Cebranopadol: An Assessment for Its Biased Activation Potential at the Mu Opioid Receptor by DFT, Molecular Docking and Molecular Dynamic Simulation Studies
3个月前
已关闭
Golidocitinib, a selective JAK1 tyrosine-kinase inhibitor, in patients with refractory or relapsed peripheral T-cell lymphoma (JACKPOT8 Part B): a single-arm, multinational, phase 2 study
3个月前
已完结
Central IRAK-4 kinase inhibition for the treatment of pain following nerve injury in rats
3个月前
已完结